Hemidesmus indicus is a pharmacologically important plant. Shahid chatha, shahzad ali, department of applied chemistry. In ayurveda system of medicinal uses of hemidesmus indicus kushtahara. Hie was analyzed by lcms to determine its phytochemical composition. Wound healing activity of hemidesmus indicus formulation. The history of its medicinal importance dates back to ancient times. Antioxidant and antihepatotoxic activities of hemidesmus indicus r. There is a growing interest in use of natural antioxidants instead of synthetic antioxidants due to its versatile health benefits. Sariva is known as indian sarsaparilla hemidesmus indicus. Hemidesmus indicus root 6 introduction hemidesmus indicus linn. Modulation of biochemical parameters by hemidesmus indicus in cumene hydroperoxideinduced murine skin. Roots of this taxon has been used in folk medicine as well as in ayurvedic and unani preparations. Evaluation of phytochemical composition and antioxidative.
The order of antioxidant potential according to ftc assay was found to be highest in plumbago zeylanica followed by holarrhena antidysenterica, acorus calamus and hemidesmus indicus. Ccl 4 and paracetamol induced hepatic damage can be cured upto an extent too by h. Abstract natural products represent a reservoir of diverse templates and are being tapped to outsource novel anticancer agents. The in vitro experiment by the disc diffusion method established that hemidesmus indicus root extracts posses a bioactive compound, which inhibits the growth of the microorganisms. Pharmacognostical and phytochemical studies of hemidesmus. Cleavage of the ester linkage generated a fragment at mlz 129. In the present study, antioxidant activity of methanolic extract. Determination of antimicrobial, cytotoxic and antioxidant. They were taxonomically identified and certified by the botanist. Request pdf antioxidant activity of roots of hemidesmus indicus the antioxidant property of roots of hemidesmus indicus l. A comparative study on the antioxidant activity of. Aug 12, 2019 antioxidant activity of hemidesmus indicus pdf the methanolic extract of hemidesmus indicus l asclepiadaceae roots was found to inhibit lipid peroxidation and scavenge hydroxyl and superoxide.
The aim of the study is to determine the antibacterial activity of cedrus deodara oil and ricinus communis oil against the gram positive bacteria staphylococcus. Antibacterial activity of the root extracts of hemidesmus. Jul 11, 2019 the root bark also possess antioxidant activity ravishankara et al. Asclepiadaceae roots was found to inhibit lipid peroxidation and scavenge hydroxyl and superoxide radicals in vitro. Periplocaceae is being used widely in ayurvedic medicine. The total phenol content was calculated using gallic acid as standard. It is endemic to peninsular india and known by its names of maredu kommulu, nannari kommulu or madina kommulu in telugu, makali beru or vagani beru in kannada and magali kizhangu in tamil is a plant whose root is used in ayurvedic medicines and for use in pickles and to make sharbat the english name of swallowroot is. Apocynaceae plant parts were collected in tiruvannamalai district of tamil nadu. Phytochemical investigation of hemidesmus indicus r.
It is endemic to peninsular india and known by its names of maredu kommulu, nannari kommulu or madina kommulu in telugu, makali beru or vagani beru in kannada and magali kizhangu in tamil is a plant whose root is used in ayurvedic medicines and for use in pickles and to make sharbat. Modulation of apoptosis in human hepatocellular carcinoma. Antibacterial activity of leaf extracts of adhatoda vasica mahe digital repository the plant is reported to show abortifacient 7, antimicrobial 89, and antitussive activities 10. Though the extracts of these plants were found to be antimicrobial in nature and have the potential to be used in clinics, the mechanism of action of is not reported. Cytotoxicity, antioxidant activity, antiinflammatory activity, and up regulation of p53 and p21 activities are considered to be some of the possible. A comparative study on the antioxidant activity of methanolic. In ayurveda, it has been used medicinally to treat stomach problems, to cure rashes and to calm the mind and induce trance states and deep meditation. Antidiarrhoeal effects of methanolic root extract of.
The antioxidant activities were determined by total antioxidant capacity, dpph 1,1diphenyl2picrylhydrazine radical scavenging assay, hydroxyl radical scavenging assay, ferrous reducing antioxidant capacity and lipid peroxidation inhibition assay methods. The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader if you would like more information about how to print, save, and work with pdfs, highwire press provides a helpful frequently asked questions about pdfs alternatively, you can download the pdf file directly to your computer, from where it. The traditional indian medicine and the use of plant drugs against various diseases receive considerable attention nowadays. African journal of microbiology research 2009 dec 3. Hemidesmus indicus is known in ayurvedic medicine as sugandi, and it has been valued for its medicinal properties for almost a thousand years. They have been prescribed against the diseases of blood, inflammation. In the present study, antioxidant activity of methanolic extract of h. Antioxidant potential some medicinal plants of central india. The phytochemical constituents of methanolic extract of h. Phytochemical profiling and in vitro screening for. The root extracts of hemidesmus indicus in different ratios of petroleum ether and ethyl acetate, tests have shown significant zone of inhibition to all. Antioxidant activity of roots of hemidesmus indicus. Antioxidant and antihyperlipidemic activity of hemidesmus indicus ajp, vol.
The concentrations needed to scavenge hydroxyl and superoxide radicals were 73. Buchanania axillaris, hemidesmus indicus and rhus mysorensis. Effect of hemidesmus indicus root extract on the blood glucose level in alloxan induced diabetic rats. Antibacterial activity of watersoluble extract from pine needles of cedrus deodara. Roots 2391 23 21 19 17 15 24 3j 29 28 1 rh 1a r me 0 or a. As the extract is known to have antimicrobial activity, our present study was designed to determine the wound healing activity of a herbal formulation made from h. Further, preliminary phytochemical analysis and tlc fingerprint profile of the extract was established to characterize the extract which showed.
Antioxidant and antihepatotoxic activities of hemidesmus. Evaluation of antioxidant and antiacne properties of terpenoidal. The aim of the study was to evaluate the antioxidant, hypoglycaemic and hypolipidemic potential of methanolic extract of roots of hemidesmus indicus hie in streptozotocin stz induced diabetic mice. Hemidesmus indicus is a perennial, fastgrowing thin creeper vine that sends tendrils out at every node to cling to the surrounding vegetation for stability and support. Aug 04, 2019 hashim and indira balachandran, lupeol acetate isolated from h. Evaluation of antioxidant properties of root bark of hemidesmus. Phytochemical profiling and in vitro screening for anticholinesterase. In all the methods, the aqueous extract has exhibited the good scavenging activity and this arises that the plant has a potential antioxidant agent. The antioxidant properties of free and encapsulated root extract were determined by dpph, superoxide and. Among the extracts, tsb showed the highest antioxidant activity followed by trb, tf. Jun 24, 2019 pdf the present investigation was carried out to evaluate the antioxidant nature of ethanolic extract of terminalia arjuna bark eeta on.
The present study showed that an aqueous extract of hemidesmus indicus roots has potent antigenotoxic activity against cisplatininduced cytogenetic damage and is cytotoxic. Fagonia arabica is one such herb, that has multiple benefits and has its roots strongly fixed in history. Antioxidant activity of hemidesmus indicus pdf the methanolic extract of hemidesmus indicus l asclepiadaceae roots was found to inhibit lipid peroxidation and scavenge hydroxyl and superoxide. Medicinal plants are being widely used, either as single drug or in combination in health care delivery system.
Bioactive components and antioxidant properties of terminalia arjuna l. Hemidesmus free phenolic fraction hdfp and hemidesmus bound phenolic fraction hdbp have been isolated from h. A number of indian medicinal plants have been used for thousands of years in a traditional system of medicine. The present study was undertaken to evaluate the effect of terpenoidal fraction of the roots of hemidesmus indicus roots tfhi on several in vitro. Br is a twining shrub, belonging to the family asclepiadaceae. Asclepiadaceae is a well known drug in ayurveda system of medicine. Determination of antimicrobial, cytotoxic and antioxidant activity in extracts of hemidesmus indicus l. Jul 18, 2019 antibacterial activity of leaf extracts of adhatoda vasica mahe digital repository the plant is reported to show abortifacient 7, antimicrobial 89, and antitussive activities 10. Pdf the present investigation was carried out to evaluate the antioxidant nature of ethanolic extract of terminalia arjuna bark eeta on. The present work is based on the standardization of hemidesmus indicus root by pharmacognostically as per who guidelines.
Extensive epidemiological and clinical studies revealed that alzheimers disease ad and type 2 diabetes mellitus t2d are most likely to appear simultaneously in aged people as t2d is a major risk factor for ad. Plastic surgery, couching a form usess cataract surgerypuncturing to release fluids in abdomen, treatment of anal fistulas, treating fractures, amputations, cesarean sections and. Therefore, development of potential multifunctional agents for dual therapy of ad and t2d has received much attention. Although other species of this variety has been reported for its standards7 this has been the complete. The amount required for 50% inhibition of lipid peroxide formation was 217. The herbal extract has promote the release of igg by lymphocytes and also the ada activity kainthla r p, kashyap effect of hemidesmus indicus anantmool extract on igg production and adenosine deaminase activity of human lymphocytes in vitro. Evaluation of antioxidant properties of root bark of. Antioxidant activity of roots of hemidesmus indicus request pdf. Hemidesmus indicus definition of hemidesmus indicus by. Hemidesmus indicus is used to make beverages and also used in traditional medicine. Asclepiadaceae commonly called as anantamul, is a well known me dicinal plant, widely used in ayurveda, siddha and unani systems of medicine, for a variety of diseases, like rheumatism, leprosl, impotency and skin infec tions. The present study suggests that hemidesmus indicus has protective activity against arthritis and the activity might be attributed to presence of terpenoid in hydroalcoholic extract, as well as in.
Assessment of antioxidant potentials of free and bound phenolics of. Whereas there is slightly difference in activities as measured by tba method. Indian journal of leprosy fruit two straight slender narrowly cylindrical widely divergent follicles. Hemidesmus indicus, phytochemical constituents, pharmacological actions, toxicity. The leaves are very slender, smooth and oval shaped, closely resembling blades of grass, and they maintain a uniform shiny dark green color throughout the year. Antimicrobial activity of hemidesmus indicus, ficus. Food antioxidant nutrients acorn squash, pumpkin, winter squash beta carotene apples catechins apricots, cantaloupe, peaches beta carotene beans catechins, vitamin e beets anthocyanins bell peppers beta carotene, vitamin c berries anthocyanins, catechins, ellagic acid in raspberries and strawberries, resveratrol in blueberries, vitamin c. This article is from bmc complementary and alternative medicine, volume 12. Medicinal plants, antioxidant activity, chemoprevention, neurodegenerative diseases, central india.
Hashim and indira balachandran, lupeol acetate isolated from h. The antioxidant potency and phenolic content of bemidesmus free phenolic and bound phenolic fraction click here to view. A standardized polyherbal decoction of nigella sativa seeds. Studies on steroids in cultured tissues and mature plant of h. Using an in vitro thrombolytic model, tinospora cordifolia, rubia cordifolia, hemidesmus indicus, glycyrrhiza glabra linn, fagonia arabica and. The leaves are chewed and are said to be refreshing. Frontiers mechanism of antibacterial action of the. A standardized polyherbal decoction of nigella sativa seeds, hemidesmus indicus roots and smilax glabra rhizomes used traditionally in sri lanka for cancer therapy has been demonstrated previously, to have antihepatocarcinogenic potential. Antioxidant and antihyperlipidemic activity of hemidesmus. Further, preliminary phytochemical analysis and tlc fingerprint profile of the extract was established to. Antimicrobial activity, ficus bengalensis, hemidesmus indicus, pterocarpus marsupium roxb, saponins, tannins, saponins medicinal plants have been used as an exemplary source for centuries as an alternative remedy for treating human diseases because they contain numerous active constituents of therapeutic value 1. Pdf antioxidant activity of leaf extracts of hemidesmus indicus l.
1151 1103 236 416 555 1451 464 1237 62 845 144 457 501 1168 769 1555 882 1358 1540 177 1148 1060 1287 1320 10 962 1192 236 1191 935 616